Drug-induced liver injury secondary to androgenic steroid use

Authors

  • Juan sebastian Theran Leon Médico residente de medicina familiar de la universidad de Santander, Bucaramanga, Colombia
  • Laura Yibeth Esteban Badillo Médico residente de medicina familiar de la universidad de Santander, Bucaramanga, Colombia

DOI:

https://doi.org/10.47993/gmb.v47i1.800

Keywords:

hepatitis, anabolic steroids, hepatotoxicity, DILI

Abstract

The use of anabolic steroids in an illicit way is a growing problem characterized by the lack of knowledge about the potential side effects of these products. The illegal use of these products has led to an underdiagnosis of adverse events, among the most frequent being hepatotoxicity. We present the case of a mature adult male amateur athlete who was hospitalized for jaundice and drug-induced liver disease related to the use of high-dose anabolic steroids.

Prevention of drug-induced liver injury (DILI) involves educating patients taking hepatotoxic drugs about their safe use, teaching the signs and symptoms associated with liver injury, as well as educating the vulnerable population in preventing self-medication or illegal use of these substances.

Metrics

Metrics Loading ...

References

Rodríguez Alfaro, J. M., Álvarez Castillo, A., & Salas Boza, A. (2020). Esteroides anabólicos: repercusiones médicas del uso indiscriminado con fines en la mejora del rendimiento atlético. Revista Medica Sinergia, 5(7), e531. https://doi.org/10.31434/rms.v5i7.531 DOI: https://doi.org/10.31434/rms.v5i7.531

García F. Implicaciones andrológicas del abuso de esteroides androgénicos anabolizantes. Rev Int Androl. 2011;9(4):160-169. DOI: https://doi.org/10.1016/S1698-031X(11)70034-6

AlShareef S, Gokarakonda SB, Marwaha R. Anabolic Steroid Use Disorder (https://www.ncbi.nlm.nih.gov/books/NBK538174/). [Updated 2022 Jun 23]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing

Garcia-Cortes M, Robles-Diaz M, Stephens C, et al. Drug induced liver injury: an update. Arch Toxicol 2020; 94:3381. DOI: https://doi.org/10.1007/s00204-020-02885-1

Vuppalanchi R, Liangpunsakul S, Chalasani N. Etiology of new-onset jaundice: how often is it caused by idiosyncratic drug-induced liver injury in the United States? Am J Gastroenterol 2007; 102:558. DOI: https://doi.org/10.1111/j.1572-0241.2006.01019.x

Lagos-Ortiz RA, Espinoza-Flores ST, Barriga-Arriagada SE, Cifuentes-Villena I, Sobarzo A, Morales Ojeda I. Caracterización y riesgos respecto al uso ilegal de esteroides anabólicos androgénicos en deportistas. ODEP [Internet]. 20 de enero de 2022 [citado 18 de diciembre de 2023];:11-2

Pontet Yéssica, Calleri Alfonso, Hernández Nelia. Hepatotoxicidad por esteroides anabólicos androgénicos, reporte de 2 casos en Uruguay. Anfamed [Internet]. 2018 Dic [citado 2023 Dic 17] ; 5( 2 ): 116-122. DOI: https://doi.org/10.25184/anfamed2018v5n2a4

Danan G, Benichou C. Causality assessment of adverse reactions to drugs--I. A novel method based on the conclusions of international consensus meetings: application to druginduced liver injuries. J Clin Epidemiol 1993; 46: 1323-1330 DOI: https://doi.org/10.1016/0895-4356(93)90101-6

Chalasani NP, Maddur H, Russo MW, et al. ACG Clinical Guideline: Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury. Am J Gastroenterol 2021; 116:878. DOI: https://doi.org/10.14309/ajg.0000000000001259

Published

2024-06-11

How to Cite

1.
Theran Leon J sebastian, Esteban Badillo LY. Drug-induced liver injury secondary to androgenic steroid use. GMB [Internet]. 2024 Jun. 11 [cited 2026 Feb. 3];47(1):90-1. Available from: https://www.gacetamedicaboliviana.com/index.php/gmb/article/view/800

Most read articles by the same author(s)